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Exploring Sponge-Derived Terpenoids for Their Potency and Selectivity against 12-Human, 15-Human, and 15-Soybean Lipoxygenases

✍ Scribed by Amagata, Taro; Whitman, Stephanie; Johnson, Tyler A.; Stessman, Chad C.; Loo, Christopher P.; Lobkovsky, Emil; Clardy, Jon; Crews, Phillip; Holman, Theodore R.


Book ID
126919942
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
127 KB
Volume
66
Category
Article
ISSN
0163-3864

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Synthesis and Absolute Configuration of
✍ Yoshihisa Tanada; Kenji Mori 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 1 views

## Abstract (−)‐Subersic acid (**1**), a new derivative of __p__‐hydroxybenzoic acid in which the __m__‐position is substituted with a bicyclic diterpenoid, was synthesized from (__S__)‐3‐hydroxy‐2,2‐dimethylcyclohexanone and __p__‐hydroxybenzoic acid. The stereochemistry of this sponge‐derived inh