Experimental tumor targeting with radiolabeled ligands
β Scribed by Donald J. Buchsbaum
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 134 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
Approaches have been developed in animal models to increase
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High-affinity receptors expressed on the surface of some tumors can be exploited by chemically conjugating the ligand for the receptor and an antibody against immune effector cells, thus redirecting their cytolytic potential against the tumor. Ovarian carcinomas and some brain tumors express the hig