Expansion of T helper type 17 lymphocytes in patients with chronic granulomatous disease
✍ Scribed by R. Horváth; D. Rožková; J. Lašťovička; A. Poloučková; P. Sedláček; A. Šedivá; R. Špíšek
- Book ID
- 108701464
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 524 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0009-9104
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Chronic granulomatous disease (CGD) is a rare congenital disorder characterized by repeated bacterial and fungal infections. Aside from a high incidence of liver abscess, little is known about hepatic involvement in CGD. The aim of this study was to describe the spectrum of liver abnormalities seen
## Abstract Chromosome analyses were carried out in eight patients with lymphoproliferative disorders of mature T and NK cells. Three cases were characterized by an abnormal expansion of granular lymphocytes (GL), one by a lymphoma of GL with leukemic spread, and four by an OKT4‐T‐CLL In four patie