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Expanded CAG Repeats Activate the DNA Damage Checkpoint Pathway

✍ Scribed by Mayurika Lahiri; Tanya L Gustafson; Elizabeth R Majors; Catherine H Freudenreich

Book ID
116753578
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
181 KB
Volume
15
Category
Article
ISSN
1097-2765

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## Abstract We have studied the rate of DNA synthesis, cell cycle distribution, formation of γ‐H2AX, and Rad51 nuclear foci and association of Rad51 with the nuclear matrix after treatment of HeLa cells with the interstrand crosslinking agent mitomycin C (MMC) in the presence of the kinase inhibito