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Excitatory amino acid antagonists protect mice against seizures induced by bicuculline

✍ Scribed by Waldemar A. Turski; Ewa Urbanska; Marek Dziki; Jolanta Parada-Turska; Chrysanthy Ikonomidou

Book ID
115800469
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
333 KB
Volume
514
Category
Article
ISSN
0006-8993

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πŸ“œ SIMILAR VOLUMES

Excitatory amino acid antagonists protec
Excitatory amino acid antagonists protect mice against MPP+ seizures
✍ Lechoslaw Turski; David N. Stephens πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 633 KB

Administration of 1-methyl-4-phenyl-pyridinium ion (MPP') into the lateral ventricle of mice induced clonic convulsions and lethality in a dose-and agedependent manner. MPP' failed to induce seizures in 4-day-old mice, and the convulsant response to MPP+ was enhanced in aged mice. The seizures trigg