Exchange Reactions of Iodine Compounds
β Scribed by McKAY, H. A. C.
- Book ID
- 109517262
- Publisher
- Nature Publishing Group
- Year
- 1937
- Tongue
- English
- Weight
- 185 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/139283b0
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π SIMILAR VOLUMES
Halogen-metal exchange reactions are among the most powerful methods for preparing organometallic reagents. Pioneered by Wittig et al. [1] and Gilman et al., [2] the halogen-lithium exchange has become an important method for the preparation of functionalized aryl and heteroaryl lithium compounds. [
An enantioselective iodine/magnesium exchange reaction between the diiodoalkane 4 and a chiral Grignard reagent 12 has been realized at Γ 78 8C in THF. The resulting a-iodoalkylmagnesium reagents 13 are configurationally stable under these conditions and during trapping by a benzaldehyde/dimethylalu