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Examining Markers in 8q24 to Explain Differences in Evidence for Association With Cleft Lip With/Without Cleft Palate Between Asians and Europeans

✍ Scribed by Tanda Murray; Margaret A. Taub; Ingo Ruczinski; Alan F. Scott; Jacqueline B. Hetmanski; Holger Schwender; Poorav Patel; Tian Xiao Zhang; Ronald G. Munger; Allen J. Wilcox; Xiaoqian Ye; Hong Wang; Tao Wu; Yah Huei Wu-Chou; Bing Shi; Sun Ha Jee; Samuel Chong; Vincent Yeow; Jeffrey C. Murray; Mary L. Marazita; Terri H. Beaty


Book ID
112095648
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
793 KB
Volume
36
Category
Article
ISSN
0741-0395

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Genetic risk factors for nonsyndromic cl
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## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2