Examining Markers in 8q24 to Explain Differences in Evidence for Association With Cleft Lip With/Without Cleft Palate Between Asians and Europeans
β Scribed by Tanda Murray; Margaret A. Taub; Ingo Ruczinski; Alan F. Scott; Jacqueline B. Hetmanski; Holger Schwender; Poorav Patel; Tian Xiao Zhang; Ronald G. Munger; Allen J. Wilcox; Xiaoqian Ye; Hong Wang; Tao Wu; Yah Huei Wu-Chou; Bing Shi; Sun Ha Jee; Samuel Chong; Vincent Yeow; Jeffrey C. Murray; Mary L. Marazita; Terri H. Beaty
- Book ID
- 112095648
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 793 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0741-0395
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## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2