## Abstract Certain experimental manipulations with sea urchin oocytes, eggs, and early embryos result in induction of cell death. We were interested in whether or not these cells posessed functional apoptotic machinery, and whether cellular demise under certain experimental conditions is due to ac
Evolutionary conservation of DNA sequences expressed in sea urchin eggs and early embryos
β Scribed by John W. Roberts; Steven A. Johnson; Porter Kier; Terrence J. Hall; Eric H. Davidson; Roy J. Britten
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 926 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-2844
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When sea urchin eggs are pretreated with fluorescent chelate probe chlorotetracycline (CTC) and then fertilized with unlabeled sperm, a small, brightly fluorescent particle resembling the mitochondrion of free-swimming sperm both in size and fluorescent staining characteristics appears in the egg cy
## Abstract We have recently found that aphidicolin, a tetracyclic diterpeneβtetraol produced by several fungi, blocks DNA synthesis of sea urchin embryos by interfering with the activity of DNA polymerase Ξ±. These cells fail to proliferate in the presence of aphidicolin. In continuation of these