Evidence of absorption rate dependency of ibuprofen inversion in the rat
β Scribed by Saeed Sattari; Dr. Fakhreddin Jamali
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 509 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
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π SIMILAR VOLUMES
Ibuprofen is a nonsteroidal antiinflammatory agent extensively used in the treatment of pain and inflammatory disorders (1). Most pharmacokinetic studies of ibuprofen have involved healthy young male volunteers (2-6). However, patients who use ibuprofen for clinical purposes are often elderly and ma
Fig. 4-Computer $ts of actual data
Flurbiprofen is a chiral 2-arylpropionate used clinically as a racemate. Previously a significant pharmacokinetic interaction between the enantiomers of flurbiprofen has been reported in both rats and humans. The possible mechanism for this interaction was believed to involve competitive protein bin
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