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Evidence for another tumor suppressor gene at 17p13.3 distal to TP53 in hepatocellular carcinoma

✍ Scribed by Xin-Yuan Guan; Jonathan S.T. Sham; Lai-Shan Tai; Yan Fang; Hong Li; Qiwan Liang


Book ID
114135459
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
214 KB
Volume
140
Category
Article
ISSN
0165-4608

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Chromosome 17p is among the most frequently deleted regions in a variety of human malignancies including breast cancer. This study has further refined the localization of a putative tumour suppressor gene (TSG) at 17p13 distal to the TP53 gene in breast carcinomas. It was found that 73% (37 of 51) o