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Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase

✍ Scribed by Carlos Gomez-Moreno; Dale E. Edmondson


Book ID
115706798
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
625 KB
Volume
239
Category
Article
ISSN
0003-9861

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Hydrolysis of Thiamin: Evidence for Rate
✍ M.W. Washabaugh; C.C. Yang; A.D. Hollenbach; P. Chen πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 988 KB

Rate constants in the \(\mathrm{pH}\) range 3-9 for formation of the enethiolate product upon hydrolysis of \(N\left(1^{\prime}\right)\)-unprotonated ("free") thiamin (1a), \(N\left(1^{\prime}\right)\)-methylthiamin (3), oxythiamine (4), and several 3-substituted-4-methylhiazolium ions in oxygen-con