The catalytic mechanism of triosephosphate isomerase (TIM) was investigated with ab initio quantum mechanical calculations. Electrostatic interactions between the quantum mechanical active site and the protein and solvent environment were modeled using the finite difference Poission-Boltzman method.
β¦ LIBER β¦
Direct evidence for the exploitation of an .alpha.-helix in the catalytic mechanism of triosephosphate isomerase
β Scribed by Lodi, Patricia J.; Knowles, Jeremy R.
- Book ID
- 127236403
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 733 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0006-2960
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