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Evidence for Urate Hydroperoxide as an Intermediate in the Urate Oxidase Reaction

✍ Scribed by Sarma, Annamraju D.; Tipton, Peter A.


Book ID
127283167
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
36 KB
Volume
122
Category
Article
ISSN
0002-7863

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Theoretical Study of Intermediates in th
✍ Kalju Kahn πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 215 KB

The energetics of the urate oxidase reaction has been studied employing HF, MP2, and DFT calculations. Gas-phase energies of possible urate oxidase reaction intermediates were calculated; radical species and dehydrourate had high relative energies while 5-hydroperoxyisourate was stable in the gas ph