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Evidence for a polytopic form of the E1 envelope glycoprotein of Hepatitis C virus

✍ Scribed by Christopher T. Migliaccio; Kathryn E. Follis; Yoshiharu Matsuura; Jack H. Nunberg

Book ID
116967407
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
530 KB
Volume
105
Category
Article
ISSN
0168-1702

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The hepatitis C virus (HCV) envelope glycoprotein E1 has been widely employed as a potential vaccine antigen in clinical research. A truncated form (amino acids 192-326) of the E1 protein (E1y) was expressed in the yeast Hansenula polymorpha and purified from the cell lysate. E1y forms protein parti