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Evaluation of the role of prolyl endopeptidase and pyroglutamyl peptidase I in the metabolism of LHRH and TRH in brain

✍ Scribed by M. Mendez; C. Cruz; P. Joseph-Bravo; S. Wilk; J.L. Charli

Book ID
119073872
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
806 KB
Volume
17
Category
Article
ISSN
0143-4179

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πŸ“œ SIMILAR VOLUMES

Evidence for pyroglutamyl peptidase I an
Evidence for pyroglutamyl peptidase I and prolyl endopeptidase activities in the rat insulinoma cell line RINm 5F: lack of relationship with TRH metabolism
✍ Paul Salers; L'Houcine Ouafik; Pierre Giraud; Anne Dutour; Jean-Yves Maltese; Ch πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 805 KB

Thyrotropin-Releasing hormone (TRH)-degrading pyroglutamyl peptidase I (PGP I) and prolylendopeptidase (PE) activities have been demonstrated in rat insulinoma RINm 5F cell line. These two enzymes catalyze the conversion of TRH to Histydyl-Proline-Diketopiperazine and to acid TRH respectively. After