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Ontogeny of prolyl endopeptidase and pyroglutamyl peptidase I in rat tissues

✍ Scribed by Naiara Agirregoitia; Luis Casis; Javier Gil; Fátima Ruiz; Jon Irazusta


Book ID
116857897
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
254 KB
Volume
139
Category
Article
ISSN
0167-0115

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Evidence for pyroglutamyl peptidase I an
✍ Paul Salers; L'Houcine Ouafik; Pierre Giraud; Anne Dutour; Jean-Yves Maltese; Ch 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 805 KB

Thyrotropin-Releasing hormone (TRH)-degrading pyroglutamyl peptidase I (PGP I) and prolylendopeptidase (PE) activities have been demonstrated in rat insulinoma RINm 5F cell line. These two enzymes catalyze the conversion of TRH to Histydyl-Proline-Diketopiperazine and to acid TRH respectively. After