The developmental toxicity of thalidomide was evaluated using FETAX (Frog Embryo Teratogenesis Assay - Xenopus). Young X. Laevis embryos were exposed to this compound in each of two concentration-response experiments with and without differently induced exogenous metabolic activation systems (MASs)
Evaluation of the Developmental Toxicity of Caffeine and Caffeine Metabolites using the Frog Embryo Teratogenesis Assay—Xenopus (FETAX)
✍ Scribed by D.J. Fort; E.L. Stover; T.L. Propst; B.C. Faulkner; T.A. Vollmuth; F.J. Murray
- Book ID
- 117451334
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 296 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0278-6915
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## Abstract Frog Embryo Teratogenesis Assay—__Xenopus__ (FETAX) is a 4‐day, alternative developmental toxicity assay designed to pre‐screen chemicals and environmental mixtures. An approach used in the scoring of FETAX results, which focuses on the determination of characteristic abnormalities indu
The Frog Embryo Teratogenesis Assay-Xenopus (FETAX) was used to assess the teratogenic potential of four solvents. Embryos of the South African clawed frog, Xenopus laevis, were exposed for 96 h to ethanol, dimethyl sulfoxide (DMSO), formamide or glycerol formal. Exposure groups were maintained usin