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Assessing the predictive validity of frog embryo teratogenesis assay—Xenopus (FETAX)

✍ Scribed by Douglas J. Fort; Enos L. Stover; Donna R. Farmer; Joan K. Lemen


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
289 KB
Volume
20
Category
Article
ISSN
0270-3211

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The developmental toxicity of thalidomide was evaluated using FETAX (Frog Embryo Teratogenesis Assay - Xenopus). Young X. Laevis embryos were exposed to this compound in each of two concentration-response experiments with and without differently induced exogenous metabolic activation systems (MASs)