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Evaluation of novel99mTc(I)-labeled homobivalent α-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting

✍ Scribed by Maurício Morais; Paula D. Raposinho; Maria Cristina Oliveira; João D. G. Correia; Isabel Santos

Book ID: 113052780
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 451 KB
Volume: 17
Category: Article
ISSN: 1432-1327
DOI: 10.1007/s00775-011-0871-y

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## Abstract Following the first synthesis of tritiated α‐melanocyte‐stimulating hormone (α‐MSH, α‐melanotropin) in 1974 by Medzihradszky __et al.__, several α‐MSH analogs were designed containing between 2 and 12 tritium atoms, the latter of which displayed a specific radioactivity of 12.21 GBq/μmo