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A 99mTc(CO)3-labeled pyrazolyl–α-melanocyte-stimulating hormone analog conjugate for melanoma targeting

✍ Scribed by Paula D. Raposinho; João D.G. Correia; Susana Alves; Maria F. Botelho; Ana C. Santos; Isabel Santos


Book ID
116799155
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
541 KB
Volume
35
Category
Article
ISSN
0969-8051

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## BACKGROUND. Previous studies have shown that the compact structure of a rhenium-cyclized ␣-melanocyte-stimulating hormone peptide analog, [Cys 3,4,10 ,D- Phe 7 ]␣-MSH 3-13 , or Re-CCMSH, significantly enhanced its in vivo tumor uptake and retention. In this study, the metal chelate 1,4,7,10-tet