Aqueous extracts of 75 different traditional medicines, currently used for the treatment of various human diseases in China, Japan and Indonesia, were screened for possible inhibitory activity against HIV-1 protease using fluorogenic assay. Forty extracts exhibited inhibitory activity at a concentra
Evaluation of Malian traditional medicines: screening for antimicrobial activity
✍ Scribed by R. Sanogo; G. Crisafi; M. P. Germanò; R. De Pasquale; G. Bisignano
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 78 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
The antimicrobial properties of a decoction and methanol extract of 13 plant species used in the traditional medicine of Mali, for fever and respiratory tract diseases, have been tested for in vitro antibacterial activity against clinically isolated bacterial strains: Haemophilus influenzae (6 strains); Staphylococcus aureus (5 strains); Streptococcus pneumoniae (3 strains); Streptococcus pyogenes (8 strains) and Moraxella catarrhalis (5 strains) responsible for respiratory infections.
The results obtained showed that the extracts from Anogeissus leiocarpus, Guiera senegalensis (Combretaceae) and Diospyros mespiliformis (Ebenaceae), have a significant activity against all strains of bacteria tested. Crossopteryx febrifuga and Pteolopsis suberosa showed moderate activity only against S. aureus.
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