Evaluation of long-term biochemical responses to combination therapy of interferon plus ribavirin in those infected with hepatitis C virus genotype 1b and high baseline viral load
β Scribed by Hitomi Sezaki; Fumitaka Suzuki; Yusuke Kawamura; Hiromi Yatsuji; Tetsuya Hosaka; Norio Akuta; Masahiro Kobayashi; Yoshiyuki Suzuki; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
- Book ID
- 118087830
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 112 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1386-6346
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## Abstract Patients with high viral load (β₯1.0βΓβ10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the
## Abstract An investigation was carried out to determine whether early viral monitoring could predict efficiently the virological response to combination therapy of two different regimens in treatmentβnaΓ―ve chronic hepatitis C patients infected with genotype 1b with high baseline viral load. Patie