Association of IL28B genotype and viral response of hepatitis C virus genotype 2 to interferon plus ribavirin combination therapy
β Scribed by Norio Akuta; Fumitaka Suzuki; Yuya Seko; Yusuke Kawamura; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
- Book ID
- 115559018
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 94 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0146-6615
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## Abstract Genetic polymorphisms of the interleukin 28B (IL28B) locus are associated closely with outcomes of pegylatedβinterferon (PEGβIFN) plus ribavirin (RBV) combination therapy. The aim of this study was to investigate the relationship between IL28B polymorphism and responses to therapy in pa
## Abstract For chronic hepatitis C virus (HCV) infection, evaluation of response to peginterferon (PEGβIFN) plus ribavirin (RBV) therapy based on viral kinetics is useful as an early predictor of treatment efficacy, but the underlying mechanisms of the different viral kinetics to treatment are sti