Evaluation of L6, an anti-carcinoma murine monoclonal antibody, in tumor-bearing nude mice
✍ Scribed by Lavie, Efraim; Beaumier, Paul L.; Brodzinsky, Laura; Hellström, Karl Erik; Hellström, Ingegerd
- Book ID
- 123218830
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 759 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0167-8140
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP
Nude mice carrying human squamous-cell carcinoma xenografts were given i.v. injections of radiolabelled monoclonal antibodies (Mas). MAb E 48, which reacts with squamouscell carcinomas, was labelled with i3'l, while a second control MAb of similar immunoglobulin subclass was labelled with lZ5l. Both