✦ LIBER ✦

Enhanced Tumor Localization of Radiolabeled Fab Fragments of Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Carcinoma Xenografts

✍ Scribed by Otsuji, Eigo ;Yamaguchi, Toshiharu ;Yamaoka, Nobuki ;Kato, Makoto ;Kotani, Tatsuya ;Kitamura, Kazuya ;Yamaguchi, Nozomi ;Takahashi, Toshio

Book ID: 108579705
Publisher: Wiley (Blackwell Publishing)
Year: 1993
Tongue: English
Weight: 622 KB
Volume: 84
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1993.tb02066.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Biodistribution of Neocarzinostatin Conj

Biodistribution of Neocarzinostatin Conjugated to Chimeric Fab Fragments of the Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Cancer Xenografts

✍ Otsuji, Eigo ;Yamaguchi, Toshiharu ;Yamaoka, Nobuki ;Taniguchi, Katsunori ;Kato, 📂 Article 📅 1994 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 334 KB

Increased tumor localization by monoclon

Increased tumor localization by monoclonal antibody A7 after F(ab')2 fragmentation in athymic nude mice bearing human pancreatic carcinomas

✍ Dr. Eigo Otsuji; Toshiharu Yamaguchi; Nobuki Yamaoka; Tatsuya Kotani; Hiroshi Ts 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 613 KB

## Abstract Much recent research has been directed toward the use of monoclonal antibodies (MoAbs) for the immunodetection of solid tumors. In pancreatic cancer, conventional immunoscintigraphy using intact MoAbs remains disappointing. In this study, ^125^I‐labeled F(ab')~2~ fragments produced by p

Localization of radiolabelled F(ab′)2 fr

Localization of radiolabelled F(ab′)2 fragments of monoclonal antibodies in nude mice bearing intraperitoneally growing human ovarian cancer xenografts

✍ Karan R. Moseley; Anne Battaile; Robert C. Knapp; Hidde J. Haisma 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 681 KB

The biodistribution and pharmacokinetics of 2 monoclonal antibodies (MAbs) specific for ovarian carcinoma, O C I25 and OV-TL3, were studied in nude mice bearing intraperitoneally (i.p.) growing human ovarian carcinoma xenografts of NIH:OVCAR-3. The ovarian carcinoma xenografts grew as non-adherent c

Localization of radiolabeled monoclonal

Localization of radiolabeled monoclonal antibody S74 in human scirrhous type gastric cancer xenografts in nude mice

✍ Yokota, Takashi ;Takahashi, Toshio ;Yamaguchi, Toshiharu ;Otsuji, Eigo ;Sawai, K 📂 Article 📅 1987 🏛 Springer-Verlag 🌐 English ⚖ 366 KB

Enhanced clearance of radiolabeled murin

Enhanced clearance of radiolabeled murine monoclonal antibody by a syngeneic anti-idiotype antibody in tumor-bearing nude mice

✍ Robert M. Sharkey; Otto C. Boerman; Ana Natale; David Pawlyk; Marc Monestier; Mi 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 945 KB

A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP

Localization of biotinylated monoclonal

Localization of biotinylated monoclonal antibody in nude mice bearing subcutaneous and intraperitoneal human tumour xenografts

✍ S. Pervez; G. Paganelli; A. A. Epenetos; W. J. Mooi; D. J. Evans; T. Krausz 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 466 KB

To demonstrate the precise distribution and binding of in vivo injected monoclonal antibodies on histological tumour sections, we have biotinylated our primary antibody AUA I. Biotinylated antibody was injected into nude mice bearing simultaneous subcutaneous and intraperitoneal xenografts of the hu