๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Evaluation of Dopaminergic Presynaptic Integrity: 6-[18F]Fluoro-L-Dopa Versus 6-[18F]Fluoro-L-m-Tyrosine

โœ Scribed by Doudet, D. J.; Chan, G. L.-Y.; Jivan, S.; DeJesus, O. T.; McGeer, E. G.; English, C.; Ruth, T. J.; Holden, J. E.


Book ID
110078968
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
546 KB
Volume
19
Category
Article
ISSN
0271-678X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


A within-subject comparison of 6-[18F]fl
โœ Catherine L. Gallagher; Bradley T. Christian; James E. Holden; Onofre T. Dejesus ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 268 KB

## Abstract Progression of Parkinson's disease symptoms is imperfectly correlated with positron emission tomography biomarkers for dopamine biosynthetic pathways. The radiopharmaceutical 6โ€[^18^F]fluoroโ€mโ€tyrosine is not a substrate for catecholโ€__O__โ€methyltransferase and therefore has a more favo

6-[18F]Fluoro-L-DOPA probes dopamine tur
โœ Dr. J. R. Barrio; S. C. Huang; W. P. Melega; D. C. Yu; J. M. Hoffman; J. S. Schn ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 664 KB

## 6-['8F ]Fluor~-L-DOPA (FDOPA) cerebral kinetics and metabolism were correlated in normal primates (Mucacu nemestrina) and primates with l-methyl-4phenyl-l,2,3,64etrahydropyridine (MPTP) induced unilateral Parkinsonism. Application of a tracer kinetic model to positron emission tomography (PET)

Synthesis of 6-[18F] and 4-[18F]fluoro-l
โœ Mohammad Namavari; N. Satyamurthy; Michael E. Phelps; Jorge R. Barrio ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 960 KB

The regioselective radiofluorodestannylation of 6-trimethylstannyl-L-m-tyrosine derivative 6 with [18F]F2 and [18F]acetyl hypofluorite afforded, after acid hydrolysis, 6-[18F]fluoro-L-m-tyrosine (8a) in radiochemical yields of 23 and 17%, respectively. Similarly, 4-[18F]fluoro-L-m-tyrosine (13a) was