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A within-subject comparison of 6-[18F]Fluoro-m-Tyrosine (FMT) and 6-[18F]Fluoro-l-DOPA (FDOPA) in Parkinson disease (PD)

โœ Scribed by Catherine L. Gallagher; James Holden; Brad Christian; Sandra Harding; Robert J. Nickles; Sterling Johnson


Book ID
119331313
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
119 KB
Volume
52
Category
Article
ISSN
1053-8119

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## Abstract Progression of Parkinson's disease symptoms is imperfectly correlated with positron emission tomography biomarkers for dopamine biosynthetic pathways. The radiopharmaceutical 6โ€[^18^F]fluoroโ€mโ€tyrosine is not a substrate for catecholโ€__O__โ€methyltransferase and therefore has a more favo

Rate of progression in Parkinson's disea
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## Abstract The aim of this study was to investigate the rate of progression in Parkinson's disease (PD) with 6โ€[^18^F]fluoroโ€Lโ€dopa (FDOPA) positron emission tomography (PET). We investigated 21 patients with PD and eight healthy controls. Ten of the patients were de novo at the time of the first