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6-[18F]fluoro-L-DOPA with positron emission tomography…


Book ID
116747966
Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
42 KB
Volume
6
Category
Article
ISSN
1536-1632

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Cerebral 6-[18F]fluoro-L-DOPA (FDOPA) me
✍ E.H. Danielsen; D.F. Smith; A.D. Gee; T.K. Venkatachalam; S.B. Hansen; F. Herman 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

We measured 6-[ 18 F]fluoro-L-DOPA (FDOPA) uptake and metabolism in the brain of 4-month-old female pigs (n ϭ 8) using a high-resolution positron emission tomograph (PET) in 3D mode. The mean net blood-brain clearance of FDOPA (K i D ) to striatum was 0.011 ml g -1 min -1 . Correcting for the elimin