Dopa-responsive dystonia: [18F]dopa positron emission tomography
โ Scribed by Dr. G. V. Sawle; K. L. Leenders; D. J. Brooks; G. Harwood; A. J. Lees; R. S. J. Frackowiak; C. D. Marsden
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 793 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-5134
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We measured 6-[ 18 F]fluoro-L-DOPA (FDOPA) uptake and metabolism in the brain of 4-month-old female pigs (n ฯญ 8) using a high-resolution positron emission tomograph (PET) in 3D mode. The mean net blood-brain clearance of FDOPA (K i D ) to striatum was 0.011 ml g -1 min -1 . Correcting for the elimin