The application of SIMPLISMA for the investigation of peak purity with liquid chromatography and diode array detection (LC-DAD) is proposed. SIMPLISMA is applied in the chromatographic direction, and is used to detect pure zones in the chromatogram. The performance of SIMPLISMA and of an approach ba
Evaluation of different techniques for peak purity assessment on a diode-array detector in liquid chromatography
β Scribed by H. Fabre; A. Le Bris; M.D. Blanchin
- Book ID
- 107785205
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 392 KB
- Volume
- 697
- Category
- Article
- ISSN
- 1873-3778
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π SIMILAR VOLUMES
The application of eigenstructure tracking analysis (ETA) for the detection of an impurity under a chromatographic peak is discussed. A window of size three seems to be the most adequate for this problem. Some guidelines for interpretation of the ETA plots are given. A new normalization of spectra i
## AbStlWt An algorithm for peak purity analysis based on the Gram-Schmidt orthogonalization method is described. The data are pretreated by using two different normalization techniques. The performance of this approach is investigated for liquid chromatography with photodiode-array detection (LC-
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