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Evaluation of contact sensitivity of rubber chemicals using the murine local lymph node assay

โœ Scribed by Yoshiaki Ikarashi; Toshie Tsuchiya; Akitada Nakamura


Book ID
109374071
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
655 KB
Volume
28
Category
Article
ISSN
0105-1873

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The local lymph node assay (LLNA) is used to assess the skin sensitization potential of chemicals. In the standard assay, mice are treated topically on the dorsum of both ears with test substance for 3 days. Following 2 days of rest, the initiation of the hypersensitivity response is evaluated by in