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Evaluation of anesthetic effects on parameters for the in situ rat brain perfusion technique

โœ Scribed by Christophe H Rousselle; Jeanne-Marie Lefauconnier; David D Allen

Book ID
117477208
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
239 KB
Volume
257
Category
Article
ISSN
0304-3940

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To characterize pentazocine (PTZ) transport across the blood-brain barrier (BBB), the cerebrovascular permeability-surface area product (PS(inf)) of PTZ was determined by a well-established in situ rat brain perfusion technique. The uptake kinetics of PTZ by the rat brain exhibited saturability, whi