Evaluation of a chronically isolated int
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Fred G. J. Poelma; Josef J. Tukker
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Article
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1987
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John Wiley and Sons
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English
β 470 KB
A model is described to study absorption kinetics of drugs in the unanesthetized rat. The surgical technique consists of a long-term isolation of an intestinal segment inside the animal. This isolated loop is used in perfusion experiments. In this model the effects of anesthesia and surgical trauma