Evaluation of a separation-based fiber-optic sensor for process analysis

✍ Scribed by Jason E. Dickens; Michael J. Sepaniak

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 120 KB
• Volume: 11
• Category: Article
• ISSN: 1040-7685
• DOI: 10.1002/(sici)1520-667x(1999)11:1<45::aid-mcs6>3.0.co;2-z

✦ Synopsis

A novel separation-based fiber-optic sensor SBFOS with potential for industrial process and waste analyses is described. The SBFOS is a chemical monitor that integrates the separation selectivity afforded by capillary electrophoresis with the remote and high sensitivity capabilities of laser-induced fluorescence and fiber-optic sensing. A small streamlined sensor is fabricated by mating a short separation capillary to laser-excitation and emission-collection fibers in a low-volume cross. Separations are performed in a zonal mode by injecting discrete volumes of sample from a contained flowing stream using a compatible sampling device. The implementation of this configuration for performing process analytical chemistry is discussed and illustrated. Two classes of analytesᎏ metal cations and aminopolycarboxylate ligandsᎏare monitored based on the formation of fluorescent complexes with 8-hydroxyquinoline-5-sulfonic acid, which is added on-line without contaminating the sample stream. The observed analytical figures of merit include relative standard deviations of 4.8% and 2.7% for peak Ž 2q .

4 intensity and migration time Mg , respectively, efficiencies of approximately 10 theoretical plates, and metal and ligand limits of detection in the parts per billion range.