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Evaluation of a high-performance thin-layer chromatographic technique for the determination of salbutamol serum levels in clinical trials

✍ Scribed by A.M. Le Roux; C.A. Wium; J.R. Joubert; P.P. Van Jaarsveld

Publisher
Elsevier Science
Year
1992
Weight
274 KB
Volume
581
Category
Article
ISSN
0378-4347

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A high-performance liquid chromatographic method was developed to determine stobadin pharmacokinetics in dog and man. The relative bioavailability of stobadin dipalmitate compared with dihydrochloride was 46.4 per cent in dog. In man peak serum concentrations ranged from 12 to 289 ng ml-1 after a si