Ethyl 1,4-dihydro-4-oxo-3-quinolinecarbo
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Richard A. Bunce; Eric J. Lee; Matthew T. Grant
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Article
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2011
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Journal of Heterocyclic Chemistry
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English
⚖ 196 KB
## Abstract The ethyl 1,4‐dihydro‐4‐oxo‐3‐quinolinecarboxylate ring structure, important in several drug compounds, has been prepared in two steps from ethyl 2‐(2‐fluorobenzoyl)acetate. Treatment of this β‐ketoester with __N__,__N__‐dimethylformamide dimethyl acetal gives a 97% yield of the 2‐dimet