Ethanol inhibits the formation of endoperoxide metabolites in human platelets
β Scribed by Hwang, Daniel H.
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 157 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0161-4630
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The incubation of human platelets with methylglyoxal and glucose produces a rapid transformation of the ketoaldehyde to D-lactate by the glyoxalase system and a partial reduction in GSH. Glucose utilization is affected at the level of the glycolytic pathway. No effect of the ketoaldehyde on glycogen