๐”– Bobbio Scriptorium
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Ethanol inhibits the activity of the B form of monoamine oxidase in human platelet and brain tissue

โœ Scribed by Boris Tabakoff; John M. Lee; Frank Leon-Jones; Paula L. Hoffman

Publisher
Springer
Year
1985
Tongue
English
Weight
595 KB
Volume
87
Category
Article
ISSN
0033-3158

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โœฆ Synopsis

Ethanol selectively inhibits the activity of the Bform of monoamine oxidase (MAO) in membranes obtained from human platelet and brain. When endogenous concentrations of phenylethylamine are used as substrate, significant inhibition is induced by concentrations of ethanol that are attainable after ethanol ingestion (50 raM). The mechanism of ethanol's inhibition of MAO activity appears to involve perturbation of membrane lipids surrounding the enzyme.

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The effects of adrenaline injections on
The effects of adrenaline injections on human platelet monoamine oxidase and related measures
โœ V. Gentil; R. L. McCurdy; B. Alevizos; M. H. Lader ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› Springer ๐ŸŒ English โš– 507 KB

A double-blind, placebo-controlled, cross-over study in ten normal volunteers assessed the effects of the subcutaneous administration of adrenaline on platelet MAO activity, in an attempt to replicate previous findings of increased MAO activity following adrenaline. Platelet counts, cortisol plasma