✦ LIBER ✦

Ethanol-induced inhibition of hepatic uptake of propranolol in perfused rat liver and in man

✍ Scribed by P. Dorian; E. M. Sellers; H. L. Kaplan; G. Carruthers; C. Hamilton; V. Khouw

Publisher: Springer
Year: 1984
Tongue: English
Weight: 967 KB
Volume: 27
Category: Article
ISSN: 0031-6970
DOI: 10.1007/bf00544047

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Endogenous nitric oxide attenuates ethan

Endogenous nitric oxide attenuates ethanol-induced perturbation of hepatic circulation in the isolated perfused rat liver

✍ Masahide Oshita; Yoshiyuki Takei; Sunao Kawano; Taizo Hijioka; Eiji Masuda; Mori 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 543 KB

The purpose of this study was to clarify the role of endogenous nitric oxide in ethanol-induced perturbation of microcirculation and hepatic injury in perfused rat liver. Infusion of ethanol into the portal vein at 25 and 100 mmol/L increased portal pressure, which is an indicator of hepatic vasocon

Product inhibition and dose-dependent bi

Product inhibition and dose-dependent bioavailability of propranolol in the isolated perfused rat liver preparation

✍ Hany Ghabrial; Romina Nand; Cheryl K. Stead; Richard A. Smallwood; Denis J. Morg 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 641 KB

Acute effects of ethanol on hepatic upta

Acute effects of ethanol on hepatic uptake and distribution of narcotics in the isolated perfused rabbit liver

✍ Mary Jeanne Kreek; Marcus A. Rothschild; Murray Oratz; Joseph Mongelli; Anne C. 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 545 KB

Insulin-dependent inhibition of hepatic

Insulin-dependent inhibition of hepatic glycogenolysis by gastric inhibitory polypeptide (GIP) in perfused rat liver

✍ H. Hartmann; R. Ebert; W. Creutzfeldt 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 354 KB

The effect of porcine gastric inhibitory polypeptide on hepatic glycogen metabolism was investigated in the isolated in situ perfused rat liver. Glycogenolysis was stimulated by infusion of glucagon into the portal vein (half maximal effective portal vein concentration -30 pmol/1). When glucagon was

Evaluation of hepatic metabolism of sali

Evaluation of hepatic metabolism of salicylic acid in perfused rat liver

✍ Bhasker V. Shetty; Mostafa Badr; Srikumaran Melethil 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 220 KB 👁 2 views

Hepatic metabolism of salicylic acid was studied using a single-pass liver perfusion technique. Livers obtained from male, Sprague-Dawley rats (200-300 g) were perfused with Krebs-Henseleit bicarbonate buffer containing the drug (50-100 micrograms/mL) and glycine (0.5 or 5 mM) or glucose (5.5 mM) or

Dose-dependent inhibition of transporter

Dose-dependent inhibition of transporter-mediated hepatic uptake and biliary excretion of methotrexate by cyclosporine A in an isolated perfused rat liver model

✍ Ridhi Parasrampuria; Reza Mehvar 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB 👁 1 views

Methotrexate (MTX) and cyclosporine (CyA) are coadministered in a number of diseases. In this study, the effects of CyA on the hepatobiliary disposition of MTX were investigated in an isolated perfused rat liver model. A bolus 5-mg dose of MTX was added to a recirculating perfusate in the absence or