Methotrexate (MTX) and cyclosporine (CyA) are coadministered in a number of diseases. In this study, the effects of CyA on the hepatobiliary disposition of MTX were investigated in an isolated perfused rat liver model. A bolus 5-mg dose of MTX was added to a recirculating perfusate in the absence or
Product inhibition and dose-dependent bioavailability of propranolol in the isolated perfused rat liver preparation
β Scribed by Hany Ghabrial; Romina Nand; Cheryl K. Stead; Richard A. Smallwood; Denis J. Morgan
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 641 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0022-3549
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