Acute effects of ethanol on hepatic uptake and distribution of narcotics in the isolated perfused rabbit liver
β Scribed by Mary Jeanne Kreek; Marcus A. Rothschild; Murray Oratz; Joseph Mongelli; Anne C. Handley
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 545 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Liver Perfusion Preparation of livers was performed according to previously reported techniques 21 with described modifications. To prevent variable lactate concentrations in the influent perfusate, erythrocytes were not added to the perfusion media. Thus, the flow rate of perfusion had to be i
Lidocaine metabolism appears to be significantly impaired by liver dysfunction of varying pathogeneses (1,2). The responsible mechanisms are subject to debate
The purpose of this study was to clarify the role of endogenous nitric oxide in ethanol-induced perturbation of microcirculation and hepatic injury in perfused rat liver. Infusion of ethanol into the portal vein at 25 and 100 mmol/L increased portal pressure, which is an indicator of hepatic vasocon
We studied the effects of a series of vasodilators on intrahepatic vascular resistance of isolated perfused cirrhotic rat livers in basal conditions and during norepinephrine-induced vasoconstriction. Cirrhosis was induced by repeated intraperitoneal injections of carbon tetrachloride. The vasodilat