๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effect of hypoxia on the hepatic metabolism of lidocaine in the isolated perfused pig liver

โœ Scribed by Dr. Berend Mets; Rosemary Hickman; Rosemary Allin; Jean van Dyk; Zoe Lotz


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
890 KB
Volume
17
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

โœฆ Synopsis


Lidocaine metabolism appears to be significantly impaired by liver dysfunction of varying pathogeneses (1,2). The responsible mechanisms are subject to debate


๐Ÿ“œ SIMILAR VOLUMES


Hepatic extraction, metabolism, and bili
โœ Christian Farabos; Marie-Christine Haaz; Pierre Gires; Jacques Robert ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 199 KB ๐Ÿ‘ 2 views

Irinotecan (CPT-11) is a semisynthetic derivative of camptothecine that has proved activity in the treatment of colorectal carcinoma. The metabolites identiยฎed in humans include SN-38, SN-38 glucuronide, and several CYP3A-derived metabolites. We have studied the hepatic extraction, metabolism, and b

Metabolic effects of acetaminophen. Stud
โœ Ana Maria Itinose; Marlene Leiko Doi Sakuno; Adelar Bracht ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 989 KB

The effects of acetaminophen on the metabolism of the isolated perfused rat liver were investigated. The following results were obtained: (1) Acetaminophen increased glucose release and glycolysis from endogenous glycogen (glycogenolysis). (2) Oxygen uptake, gluconeogenesis from either pyruvate or

Effect of vasodilators on hepatic microc
โœ Philippe Marteau; Franรงois Ballet; Olivier Chazouillรจres; Yves Chrรฉtien; Colette ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 489 KB ๐Ÿ‘ 1 views

We studied the effects of a series of vasodilators on intrahepatic vascular resistance of isolated perfused cirrhotic rat livers in basal conditions and during norepinephrine-induced vasoconstriction. Cirrhosis was induced by repeated intraperitoneal injections of carbon tetrachloride. The vasodilat

The action of zymosan on octanoate trans
โœ Alice M. Derbocio; Carlos H. Lopez; Lรญvia Bracht; Adelar Bracht; Emy L. Ishii-Iw ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 196 KB ๐Ÿ‘ 2 views

## Abstract The effects of zymosan on transport, distribution, and metabolism of octanoate in the perfused rat liver were investigated using the multipleโ€indicator dilution technique. Livers were perfused with 300 ยตM octanoate in the absence or in the presence of 100 ยตg/mL zymosan. Tracer amounts o