In perfused livers from fed rats, rates of glucose production (glycogenolysis) were 133 f 12 pmollglhr. Infusion of 2 pM verapamil into these livers decreased the rates of glucose production significantly to 97 \* 15 pmollglhr within 10 min. Conversely, rates of production of lactate plus pyruvate (
Acute effect of leptin on hepatic glycogenolysis and gluconeogenesis in perfused rat liver
✍ Scribed by Martin Nemecz; Kurt Preininger; Rainer Englisch; Clemens Fürnsinn; Barbara Schneider; Wernes Waldhäusl; Michael Roden
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 172 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0270-9139
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✦ Synopsis
Liver Perfusion
Preparation of livers was performed according to previously reported techniques 21 with described modifications. To prevent variable lactate concentrations in the influent perfusate, erythrocytes were not added to the perfusion media. Thus, the flow rate of perfusion had to be increased to provide for sufficient oxygen supply
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