## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
β¦ LIBER β¦
Estrone Formate: A Novel Type of Irreversible Inhibitor of Human Steroid Sulfatase.
β Scribed by Erwin P. Schreiner; Andreas Billich
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 73 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Estrone sulfate (E1S) is an endogenous prodrug that delivers estrone and, subsequently, estradiol to target cells, after hydrolysis by the enzyme estrone sulfatase, which is active in various tissues including hormoneβdependent breast cancer. Blockade of this enzyme should reduce the es
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