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Estimation of Population Pharmacokinetic Parameters of Saquinavir in HIV Patients with the MONOLIX Software

✍ Scribed by Marc Lavielle; France Mentré

Book ID
106423453
Publisher
Springer
Year
2007
Tongue
English
Weight
367 KB
Volume
34
Category
Article
ISSN
1573-8744

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Using simulated viral load data for a given maraviroc monotherapy study design, the feasibility of different algorithms to perform parameter estimation for a pharmacokinetic-pharmacodynamic-viral dynamics (PKPD-VD) model was assessed. The assessed algorithms are the first-order conditional estimatio