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Estimation of Population Pharmacokinetic Parameters in the Presence of Non-compliance

✍ Scribed by Song Mu; Thomas M. Ludden


Book ID
110433836
Publisher
Springer
Year
2003
Tongue
English
Weight
389 KB
Volume
30
Category
Article
ISSN
1573-8744

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In clinical trials where patients are randomized between two treatment arms, not all patients comply with the treatment they were randomly assigned to. The reasons for (non)compliance may be associated with the outcome variable and thereby act as confounders. The standard way of analysing such trial