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Population pharmacokinetics of lopinavir in combination with ritonavir in HIV-1-infected patients

✍ Scribed by K. M. L. Crommentuyn; B. S. Kappelhoff; J. W. Mulder; A. T. A. Mairuhu; E. C. M. Van Gorp; P. L. Meenhorst; A. D. R. Huitema; J. H. Beijnen


Book ID
108641405
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
265 KB
Volume
60
Category
Article
ISSN
0306-5251

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## Abstract The HIV‐1 protease L76V mutation has been described recently as conferring high‐level resistance to lopinavir/ritonavir (LPV/r). The aim was to identify the factors and particularly protease mutations associated with the presence of L76V in treatment‐experienced patients infected with H