A novel approach to the analysis of acylcarnitines has been developed. It involves a direct esterification using propyl chloroformate in aqueous propanol followed by ion-pair extraction with potassium iodide into chloroform and subsequent on-column N-demethylation of the resulting acylcarnitine prop
Estimation of N-amino-N,N-dimethylaminoethanol, choline and their acetate esters by gas chromatography mass spectrometry
β Scribed by M.W. Newton; B. Ringdahl; D.J. Jenden
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 510 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
β¦ Synopsis
A method is described for measurement of choline, N-aminodeanol, and their acetyl esters by gas chromatography mass spectrometry. The preparation of N-aminodeanol and its isotopic variants is also described. This method allows a thorough quantitative analysis of the replacement of true with false neurotransmitter in biological preparations.
π SIMILAR VOLUMES
## Abstract __N__(Pyrimidinβ2βyl)βglycine, βalanine and βphenylalanine (1β3) and their methyl esters (4β6) were investigated using electron impact (EI) mass Spectrometry. The results showed that EIβinduced decomposition occurs on the carboxylic group or involves the loss of R~2~OH. In contrast to e