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Estimation of haplotype frequencies

✍ Scribed by NEWTON E MORTON; S. PATRICIA SIMPSON; RUTH LEW; SHIRLEY YEE

Book ID
115093521
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
307 KB
Volume
22
Category
Article
ISSN
0001-2815

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πŸ“œ SIMILAR VOLUMES

Estimation of myriad haplotype frequenci
Estimation of myriad haplotype frequencies
✍ Charles J. Maclean; Newton E. Morton; D. C. Rao πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 605 KB

The present paper demonstrates algorithms for applying gene counting estimation of haplotype frequencies in very large genetic systems. A factor union representation of phenotypes is used which conveniently yields the sets of potential haplotypes and diplotypes for each phenotype. Methods for storin

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## Abstract The importance of haplotype analysis in the context of association fine mapping of disease genes has grown steadily over the last years. Since experimental methods to determine haplotypes on a large scale are not available, phase has to be inferred statistically. For individual genotype

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The program which is written in FORTRAN estimates haplotype frequencies in two-locus and three-locus genetic systems from population diploid data. It is based on the gene counting method which leads to maximum likelihood estimates, and can be used whenever the possible antigens (one or more) on each