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A general program for estimation of haplotype frequencies from population diploid data

โœ Scribed by S.Olesen Larsen

Publisher
Elsevier Science
Year
1979
Weight
560 KB
Volume
10
Category
Article
ISSN
0010-468X

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โœฆ Synopsis

The program which is written in FORTRAN estimates haplotype frequencies in two-locus and three-locus genetic systems from population diploid data. It is based on the gene counting method which leads to maximum likelihood estimates, and can be used whenever the possible antigens (one or more) on each chromosome can be specified for each person and for each locus, i.e., ABO-like systems and inclusions are permitted. The number of alleles per locus may be rather large, and both grouped and ungrouped data can be used. Log likelihoods are calculated on the basis of various assumptions, so that likelihood ratio tests can be carried out.

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